If you have the choice to deploy a WPF app, couldn't you ship something using chromiumembedded to get the benefits of a web app without worrying about browser compatibility? In the past, I've even dropped a CEF WebView into WPF and had the UI in HTML/CSS/JS.
But if you've already got a captive audience able to run anything .NET 4.0 and above (incl. async/await via Bcl.Async libraries) with the rich experience of WPF, why bother shoehorning a web application as a solution?
Our users are in a manufacturing environment, on a well-known environment. It's practically like developing for a gaming console. And in that light, WPF seems to be a good fit.
I have pretty limited experience with desktop stuff (mostly Winforms) but with the SPA frameworks now it's about as expressive and deployment issues go away (which is nice in a small shop where you can't just foist them on someone else).
We're able to produce a standalone desktop application and a web app using the same code and have it looking/working exactly the same, on different platforms.
