That's the traditional "business district" style downtown, yeah, but afaict there's been a shift away from that in the past 15-20 years, and now many people commute to downtown in the evenings, because that's where all the restaurants/bars/clubs/theaters are. That's definitely the case in the Bay Area, where SF is much more lively after 5pm than most of the Valley is (Santa Clara is basically dead once office workers go home). Was also the case in Midtown Atlanta when I lived there a few years ago; big influx from the suburbs in the evenings, esp on weekends.
SOMA too for the most part. Sadly the walk between workable parts (SOMA/FiDi) and livable parts has goes through areas that are less than ideal for walking (in terms of feeling safe).