There's a lot you can do with variable fonts. I remember stumbling upon https://variicon.netlify.app/index.html a year or two ago, although there's disdain for using icons as a font it was eye opening for me with what you could do.
My favorite is fonts with a "serif-ness" slider. You can dynamically switch between a serif and sans serif version of the same font. Imagine doing it all with a single font!
https://v-fonts.com/
I'll still only stick to websafe fonts for actual websites but I'm excited to see what the future holds. Also because I hate Arial