> Insomnia and ADHD medication are a dangerous combo

A few months ago I started taking 15mg diphenhydramine every night just to make damn sure I always get enough sleep. I had taken it occasionally in the past, but didn't like the lingering effect it had the next morning. Then I had a conversation with my sister, who said that she takes it every night for the antihistamine effects after a doctor told her it's fine. The morning after effects seemed to fade (or I got used to them) pretty quickly once I started regular dosing.

Of course I have mixed feelings about ratcheting up the number of medications I'm taking daily, but to be fair OTC allergy medicine is a far cry from using something like Ambien or benzos to manage insomnia.

> slavic nootropics and neuro-regenerative peptides (e.g. semax/NASA, BPC-500,

more info?

Apologies; I confused BPC-157 with TB-500, and made a horrible amalgamation.

What do you want to know? Do you have some specific goal you want achieved or curiosity that you would like satisfied?

It's been a bit since I've been involved with these things. Most of it is underground, but I can give you a quick rundown.

BPC-157 and TB-500 are regenerative peptides. BPC-157 seems to be more "global" and neuro-involved throughout the body, while TB-500 is more local and structural (joints, tendons, etc.). BPC-157 also has a (prolonged) effect in some that negates the effects of amphetamines. Subcutaneous injections of BPC-157 have helped get rid of my recurring ganglion cysts and golfer's elbow.

Semax would fall under "slavic nootropics," along with Selank, and if I remember correctly Epithalon. All have "sub-versions" of varying efficacy. F.e. all have "N-Acetyl" and "N-Acetyl Amidate" versions. NASA would be the shortened version of "N-Acetyl Semax Amidate" -- which in my experience is the "strongest." With NASA, while I was injecting it subcutaneously it brought a sort of structure to my mind I hadn't had since I was a child. It's like feeling everything is falling into place, and a loss of the feeling of helplessness.

If you've ever used noopept, it's like that except with more real and long-lasting effects. I would liken it to bromantane, too.

If not, it's difficult to explain what they are, because they're such a different class of drugs that there's no reference point to base their effects off of. Imagine that you have a drug, but instead of giving you a few hours of a noticeable "high" or "low," instead you get a small, but perceptible shift in how you view the world, and how you filter all the information coming in. Like a micro-micro-micro dose of LSD. No high, no impairment, just a beneficial "shift" in your perception that lasts for an indeterminate, but long time.

A few of my friends were career-researchers and likened these effects to be genomic (subtly altering the expression of genes all around the body) rather than physical (that is, simple physical reactions like consuming more electrolytes would cause you to hold more water, and become bloated, because electrolytes attract and "hold" water; or how drunkenness is simply a temporary shift in the delicate GABA/glutamate balance in your brain). The purely "physical" drugs require constant re-dosing to be effective, while the more genomic ones (such as peptides) can have long-lasting effects even after they've been ceased.

Looks like there's NASA sold in spray form, how would that compare in efficacy to subcutaneous injection?

Seems to act differently depending on route of administration. If you've ever had weed, it's like edibles (injecting) vs. smoking (nasal).

Intranasal is more cerebral, "in your head" type of effects.

Subq is more bodily, "all around your body" type of effects.

If you're looking at it as a nootropic, I would recommend the spray. It feels similar to prozac and wellbutrin, if they weren't so terrible.

If you're looking at is as an anodyne or body-anxiolytic, I would recommend subq. If feels like baclofen.

I guess I'm a little confused by your answer - are peptides nootropics or sensation-type experiences? I guess I perceive nootropics as like "become smarter" or "having better recall" but this answer makes it seem like a recreational time bound physical experience? I also could see how the mental and physical have blurred boundaries.

I'm nodding off right now, so my verbal fluency is off. I think I was trying to make an analogy on how their effects differ, not on how their effects are.

For example, with eating weed, you get bodily sensations, and so its effects are more on your body, i.e. physical; while with smoking weed, the "sensations" are more in your head, and mental.

Likewise, with injecting NASA, the effects seem to be spread around your body and more "physical"; while administering NASA intranasaly, the effects are more mental, and focused "in your head."

The route of administration changes the expression of the drug on your body and mind. Dependent on that, it can either be a nootropic (nasal route) or akin to a mild and sensationless (compared to painkillers like opiates) muscle relaxant (subcutaneous).

It's difficult to explain, because the effects are so mild and without the normal "Oh, I'm on drugs. I can feel it" sensations, that you can only see them in hindsight (in my case, by perusing old journal entries).

Are there short and long term benefits as far as memory and what not?

Uncertain. Likely nothing noticeable.

Only thing in the vein has been a better ability to plan, reason about in my head, and make use of visualization to reason about problems (and their solutions).