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How much of a factor is mental health in success?

Someone could be a 4th standard deviation IQ genius yet be debilitated by anxiety, depression, or some other condition.

On the flipside many successful people have credited drugs with some part of their success by boosting ambition, endurance, creativity, confidence, etc. If a Cocaine substitute was discovered that had no negative side effects, could this positively affect scientific progress?

Occasionally a mental "disability" can seemingly be related to success. So many great scientists have been on the Autistic spectrum, or suffered from severe OCD. Can the success of the person be separated from the disorder? Could "cures" for Autism and OCD actually negatively affect scientific progress?



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